Kwirinda trombus ikwirakwiza icyiciro

Ntagushidikanya ko iterambere rya anticoagulants ryateje imbere ubuvuzi bwa DVT.Ubuvuzi bwa Anticoagulant burashobora gukumira indwara ya trombus, ikabuza ikwirakwizwa rya trombus, koroshya autolysis ya trombus no guhinduranya lumen, kugabanya ibimenyetso, no kugabanya indwara nimpfu ziterwa na embolisme yimpyiko.Kugeza ubu, imiti igabanya ubukana irimo heparin, uburemere buke bwa heparin, warfarin, rivaroxaban na dabigatran.Buri miti muriyo miti ifite ibyiza byayo nibibi.Ugereranije na heparine idacitse, uburemere buke bwa molekuline heparin munsi cyangwa imitsi irashobora kugabanya cyane impfu.Muri anticagulants zo mu kanwa, warfarin ikoreshwa cyane kubera igiciro cyayo gito, ingaruka nziza ya anticoagulant murwego rwo kuvura neza (bisaba ko igipimo mpuzamahanga gisanzwe kiri hagati ya 2 na 3).Nyamara, kubera ko warfarin yibasiwe cyane nibiryo, biroroshye kugira ibibazo nka anticoagulation idahagije no kuva amaraso, kandi birakenewe gukurikirana imikorere ya coagulation buri gihe.Mu myaka yashize, umubare munini wa anticoagulants nshya wagaragaye mu buriri, nka rivaroxaban, dabigatran, apixaban, nibindi. Ingaruka ya anticoagulant nukuri, ingorane zo kuva amaraso ziragabanuka, kandi nta mpamvu yo kongera gusuzuma imikorere ya coagulation.

Kugeza ubu, intiti zimwe zivuga ko kuvura ibiyobyabwenge bishobora kugabanywamo ibice bibiri ukurikije igihe cyagenwe cy’amezi 3: icyiciro cya mbere cyitwa icyiciro cya mbere cyo kuvura.Bikorwa cyane cyane mumezi 3 nyuma ya dvt3 itangiye, naho icyiciro cya kabiri cyitwa icyiciro cyo gukumira ibyakurikiyeho, bikorwa nyuma y'amezi 3 nyuma yicyiciro cya mbere cyo kuvura.Amabwiriza ya Accp9 yabanje gusaba anticagulants zo mu kanwa.Ku nshuro ya 10 y’amabwiriza y’abanyamerika y’abaganga b’igituza (ACCP), itandukaniro rinini cyane mu bihe byashize ni uko imiti igabanya ubukana bwo mu kanwa (noac), nk'ibikoresho bya Xa inhibitor (rivaroxaban, sodium ya fondaparinux, n'ibindi) hamwe na IIA inhibitor (IIA) dabigatran, nibindi) bikoreshwa nkuburyo bwa mbere bwo kuvura VTE.Ubuvuzi bwa Anticoagulant bufite ingaruka zifatika, bugabanya cyane ibibazo byo kuva amaraso, kandi ntibisaba kongera gusuzuma imikorere ya coagulation.Irimo itezwa imbere mu barwayi basanzwe.Anticoagulants nshya irashobora kwirinda ko DVT itazongera kubaho muri 80% ~ 92%.

Intambamyi yo kuvura anticoagulant yonyine ni uko nubwo imiti igabanya ubukana ikoreshwa mu kugabanya umuvuduko wa trombus no kurinda imikorere y’imitsi y’imitsi, ntishobora gushonga vuba.Kwiyuhagira kwa trombus ntibikunze kugaragara ku barwayi barwaye imitsi ya iliofemorale, kandi trombus isigaye ishobora gutera kwangirika kw'imitsi no kwangirika kw'inzira zisohoka, zikaba ari zo mpamvu zituma abantu benshi bandura syndrome ya trombose (PTS).Ubushakashatsi bwakozwe ku byerekeranye no kubaho kwa PTS nyuma yo kuvura antivagulant ya DVT bwerekanye ko indwara ya PTS yari hafi 20% ~ 50%, indwara y’ibisebe byo mu mitsi yo mu ngingo zo hasi yari 5% ~ 10%, naho indwara yo kwanduza imitsi yari 40% nyuma yimyaka 5.Abagera kuri 15% by'abarwayi bari bafite ibibazo byo kugenda, kandi ubuzima bw'abarwayi 100% bwaragabanutse ku buryo butandukanye.